## Abstract The title compounds were synthesized starting from dimethyl (2S,3aR,8aS)‐(+)‐8‐(phenylsulfonyl)hexahydrophyrrolo[2,3‐b]indole‐1,2‐dicarboxylate. This compound on treatment with LDA followed by reaction with [^14^C]methyl iodide or [^3^H]methyl iodide gave the methyl substituted derivati
Synthesis of two S-(methyl-3H)-labelled enkephalins and S-(methyl-14C)substance P
✍ Scribed by Kjeli Någren; Henry M. Franzèn; Ulf Ragnarsson; Bengt Långström
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- French
- Weight
- 256 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
3H-Sch 47949, racemic 3H-Sch 48461, was prepared at a specific activity of 40 mCi/mmole by Pt catalysed exchange with tritiated water. 3H-Sch 48461 was prepared at a specific activity of 64.6 Ci/mmole by a Pd/C catalysed reduction of an olefinic intermediate. 14C-Sch 48461 was prepared in 8 steps fr
## Abstract ^2^H and ^3^H labelled Sch 40120 were prepared by Pt catalysed exchange with isotopic water. D7‐Sch 40120 was obtained in two exchanges in 53% yield and ^3^H‐Sch 40120 was prepared by a single exchange at a specific activity of 19.8 Ci/mmole. ^14^C‐Sch 40120 was prepared in 4 steps from
## Abstract [^3^H]SCH 211803, at a specific activity of 1.56 Ci/mmol, was prepared by direct exchange with tritiated water and platinum metal. [^2^H~4~]SCH 211803 was prepared from [^2^H]formaldehyde in a seven step synthesis in 10% yield. [^14^C]SCH 211803 was prepared from __N__‐benzyl‐4‐hydroxy[
## Abstract ^3^H‐Sch 58235 was prepared at a specific activity of 29.1 Ci/mmol by Ir(COD)(Cy~3~P)PyPF~6~ catalysed exchange with tritium gas. ^14^C‐Sch 58235 was prepared in three steps from __p__‐hydroxy[ring‐U‐^14^C]benzaldehyde with an overall radiochemical yield of 21%. ^13^C~6~‐Sch 58235 was s