✦ LIBER ✦

Synthesis of 2H, 3H and 14C labelled Sch 40120

✍ Scribed by D. Hesk; T. Duelfer; S. Hickey; D. Hochman; D. Koharski; P. McNamara; S. Saluja

Publisher: John Wiley and Sons
Year: 1994
Tongue: French
Weight: 376 KB
Volume: 34
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580340714

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✦ Synopsis

Abstract

^2^H and ^3^H labelled Sch 40120 were prepared by Pt catalysed exchange with isotopic water. D7‐Sch 40120 was obtained in two exchanges in 53% yield and ^3^H‐Sch 40120 was prepared by a single exchange at a specific activity of 19.8 Ci/mmole. ^14^C‐Sch 40120 was prepared in 4 steps from ^14^C‐m‐chloro aniline in overall 16% radiochemical yield.

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