𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Steady-state volume of distribution after multiple doses

✍ Scribed by William L. Hayton; Peter Haefelfinger

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
100 KB
Volume
74
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Noncompartmental determination of the me
Noncompartmental determination of the mean residence time and steady-state volume of distribution during multiple dosing
✍ Haiyung Cheng; William J. Jusko πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 233 KB πŸ‘ 1 views

Moment analysis has become widely used in recent years as a noncompartmental approach to the estimation of mean residence time (MRT) and steady-state volume of distribution (Vd,,) from single-dose data.1-5 In 1983, the method was first extended to the multiple-dosing situation by Bauer and Gibaldi.6

Noncompartmental determination of the st
Noncompartmental determination of the steady-state volume of distribution
✍ Leslie Z. Benet; Renato L. Galeazzi πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 English βš– 474 KB πŸ‘ 1 views

## Melting Point 0 1 2 R 2420 202-203O 19O-l9l0 lfin-Ifi2~ para-substituted phenyl and substituted alkyl moieties and the sum of AH, contributions of each functional group present in the R moiety in the ester. Some important AH, values used in our study are shown in Table I (2). A straightforward a

Steady-state distribution volume in phys
Steady-state distribution volume in physiologic multi-organ systems
✍ Michael Weiss πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 English βš– 298 KB

## Abstract A unique definition of the apparent volume of distribution at steady‐state is presented which is consistent with the realistic concept of blood concentration differences within the circulatory system. A physiologically based pharmacokinetic model consisting of eliminating and non‐elimin