Model-independent steady-state volume of distribution
β Scribed by Arthur B. Straughn
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 250 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0022-3549
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π SIMILAR VOLUMES
## Melting Point 0 1 2 R 2420 202-203O 19O-l9l0 lfin-Ifi2~ para-substituted phenyl and substituted alkyl moieties and the sum of AH, contributions of each functional group present in the R moiety in the ester. Some important AH, values used in our study are shown in Table I (2). A straightforward a
## Abstract A unique definition of the apparent volume of distribution at steadyβstate is presented which is consistent with the realistic concept of blood concentration differences within the circulatory system. A physiologically based pharmacokinetic model consisting of eliminating and nonβelimin
The volume of distribution at steady state is considered to be one of the primary pharmacokinetic measurements obtained from in vivo experiments. This quantity is quite commonly calculated using moments of the observed concentration curve, the process being referred to as noncompartmental analysis.