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Asymmetric synthesis of a nitroalkane by the use of novel nitroalkene reductases from baker's yeast

✍ Scribed by Yasushi Kawai; Yoshikazu Inaba; Motoko Hayashi; Norihiro Tokitoh

Publisher: Elsevier Science
Year: 2001
Tongue: French
Weight: 50 KB
Volume: 42
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)00464-6

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✦ Synopsis

Two kinds of novel nitroalkene reductases were isolated from baker's yeast. Reduction of a trisubstituted nitroalkene by these reductases afforded the corresponding nitroalkane with excellent enantioselectivity, moderate diastereoselectivity, and in good yield.

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