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ChemInform Abstract: Asymmetric Synthesis of β-Hydroxy Esters Having Three Consecutive Chiral Centers with a Reductase from Bakers′ Yeast.

✍ Scribed by Yasushi Kawai; Kouichi Hida; Duc Hai Dao; Atsuyoshi Ohno

Publisher: John Wiley and Sons
Year: 2010
Weight: 31 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199909040

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✦ Synopsis

Asymmetric Synthesis of β-Hydroxy Esters Having Three Consecutive Chiral Centers with a Reductase from Bakers' Yeast.

-The title reaction is investigated with β-keto esters (I) having a secondary alkyl group at the α-position. The corresponding β-hydroxy esters can be isolated in excellent enantioselectivity. -(KAWAI, YASUSHI; HIDA, KOUICHI; DAO,

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