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Asymmetric synthesis of β-hydroxy esters having three consecutive chiral centers with a reductase from bakers' yeast

✍ Scribed by Yasushi Kawai; Kouichi Hida; Duc Hai Dao; Atsuyoshi Ohno


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
204 KB
Volume
39
Category
Article
ISSN
0040-4039

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ChemInform Abstract: Asymmetric Synthesi
✍ Yasushi Kawai; Kouichi Hida; Duc Hai Dao; Atsuyoshi Ohno 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

Asymmetric Synthesis of β-Hydroxy Esters Having Three Consecutive Chiral Centers with a Reductase from Bakers' Yeast. -The title reaction is investigated with β-keto esters (I) having a secondary alkyl group at the α-position. The corresponding β-hydroxy esters can be isolated in excellent enantios