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Various lengths of C-terminal fragments of amyloid precursor protein induce neurotoxicity, not only C31

✍ Scribed by Choi, Yoori; Kim, Minji; Kim, Hye-Sun; Suh, Yoo-Hun

Book ID
123184418
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
42 KB
Volume
5
Category
Article
ISSN
1552-5260

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## Abstract The AICD (APP intracellular Domain) and C31, caspase‐cleaved C‐terminal fragment of APP, have been found in Alzheimer's disease (AD) patients' brains and have been reported to induce apoptosis in neuronal cells. In recent, the C‐terminal fragments of amyloid precursor protein (APP‐CTs)