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P3-213 Inhibition of histone deacetylation enhances the neurotoxicity induced by the C-terminal fragments of amyloid precursor protein

✍ Scribed by Kim, Eun-Mee; Kim, Hye-Sun; Chang, Keun-A.; Choi, Yoori; Ahn, Kwang-Woo; Kim, Seonghan; Park, Cheol Hyoung; Suh, Yoo-Hun

Book ID
122630122
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
162 KB
Volume
25
Category
Article
ISSN
0197-4580

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Inhibition of histone deacetylation enha
Inhibition of histone deacetylation enhances the neurotoxicity induced by the c-terminal fragments of amyloid precursor protein
✍ Hye-Sun Kim; Eun-Mee Kim; Na-Jung Kim; Keun-A Chang; Yoori Choi; Kwang-Woo Ahn; 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 840 KB

## Abstract The AICD (APP intracellular Domain) and C31, caspase‐cleaved C‐terminal fragment of APP, have been found in Alzheimer's disease (AD) patients' brains and have been reported to induce apoptosis in neuronal cells. In recent, the C‐terminal fragments of amyloid precursor protein (APP‐CTs)