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Tumor M2 pyruvate kinase: a tumor marker and its clinical application in gastrointestinal malignancy

โœ Scribed by Hardt, Philip D; Ewald, Nils


Book ID
118068601
Publisher
Expert Reviews
Year
2008
Tongue
English
Weight
282 KB
Volume
8
Category
Article
ISSN
1473-7159

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Tumor type M2 pyruvate kinase (TuM2-PK)
โœ Selma Ugurel; Nellie Bell; Antje Sucker; Anette Zimpfer; Werner Rittgen; Dirk Sc ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 201 KB

## Abstract Proliferating cells express the pyruvate kinase isoenzyme type M2 (M2โ€PK). This enzyme exists as an active tetramer and an inactive dimer. The dimeric form is predominantly found in tumor cells and is therefore termed Tumor M2โ€PK (TuM2โ€PK). TuM2โ€PK molecules are released into the periph