Evaluation of the Pyruvate Kinase isoenzyme tumor (Tu M2-PK) as a tumor marker for cervical carcinoma
β Scribed by Babita Kaura; Rashmi Bagga; Feruza D. Patel
- Book ID
- 109006319
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 53 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1341-8076
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## Abstract Proliferating cells express the pyruvate kinase isoenzyme type M2 (M2βPK). This enzyme exists as an active tetramer and an inactive dimer. The dimeric form is predominantly found in tumor cells and is therefore termed Tumor M2βPK (TuM2βPK). TuM2βPK molecules are released into the periph
## Abstract Proliferating cells, particularly the tumor cells, express a dimeric isoenzyme of pyruvate kinase, termed M2βPK. It's a direct target of several oncoproteins; the determination of fecal tumor pyruvate kinase type M2 (M2βPK) might be another promising tool for colorectal cancer (CRC) scr