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Determination of pyruvate kinase type tumor M2 in human renal cell carcinoma: a suitable tumor marker?

✍ Scribed by Z., Varga ;A., Hegele ;T., Stief ;A., Heidenreich ;R., Hofmann

Book ID
105933678
Publisher
Springer
Year
2002
Tongue
English
Weight
93 KB
Volume
30
Category
Article
ISSN
0300-5623

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## Abstract Proliferating cells express the pyruvate kinase isoenzyme type M2 (M2‐PK). This enzyme exists as an active tetramer and an inactive dimer. The dimeric form is predominantly found in tumor cells and is therefore termed Tumor M2‐PK (TuM2‐PK). TuM2‐PK molecules are released into the periph