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Tumor type M2 pyruvate kinase expression in metastatic renal cell carcinoma

โœ Scribed by Roigas, J. ;Deger, S. ;Schroeder, J. ;Wille, A. ;Turk, I. ;Brux, B. ;Jung, K. ;Schnorr, D. ;Loening, S. A.


Book ID
105933749
Publisher
Springer
Year
2003
Tongue
English
Weight
195 KB
Volume
31
Category
Article
ISSN
0300-5623

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Tumor type M2 pyruvate kinase (TuM2-PK)
โœ Selma Ugurel; Nellie Bell; Antje Sucker; Anette Zimpfer; Werner Rittgen; Dirk Sc ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 201 KB

## Abstract Proliferating cells express the pyruvate kinase isoenzyme type M2 (M2โ€PK). This enzyme exists as an active tetramer and an inactive dimer. The dimeric form is predominantly found in tumor cells and is therefore termed Tumor M2โ€PK (TuM2โ€PK). TuM2โ€PK molecules are released into the periph