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The pyruvate kinase isoenzyme M2 (Tu M2-PK) as a tumour marker for renal cell carcinoma

✍ Scribed by R. WEINBERGER; B. APPEL; A. STEIN; Y. METZ; A. NEHEMAN; M. BARAK

Book ID
108710440
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
112 KB
Volume
16
Category
Article
ISSN
0961-5423

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## Abstract Proliferating cells express the pyruvate kinase isoenzyme type M2 (M2‐PK). This enzyme exists as an active tetramer and an inactive dimer. The dimeric form is predominantly found in tumor cells and is therefore termed Tumor M2‐PK (TuM2‐PK). TuM2‐PK molecules are released into the periph