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Tumor M2-pyruvate kinase: Is it a new useful marker for neuroendocrine tumors?

✍ Scribed by Pezzilli, Raffaele; Migliori, Marina; Morselli-Labate, Antonio M.; Campana, Davide; Ventrucci, Maurizio; Tomassetti, Paola; Corinaldesi, Roberto

Book ID
122768584
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
258 KB
Volume
124
Category
Article
ISSN
0016-5085

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## Abstract Proliferating cells express the pyruvate kinase isoenzyme type M2 (M2‐PK). This enzyme exists as an active tetramer and an inactive dimer. The dimeric form is predominantly found in tumor cells and is therefore termed Tumor M2‐PK (TuM2‐PK). TuM2‐PK molecules are released into the periph