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Tumor M2-Pyruvate Kinase, a New Metabolic Marker for Pancreatic Cancer

✍ Scribed by Maurizio Ventrucci; Antonio Cipolla; Chiara Racchini; Riccardo Casadei; Patrizia Simoni; Lucio Gullo

Book ID
111578964
Publisher
Springer US
Year
2004
Tongue
English
Weight
200 KB
Volume
49
Category
Article
ISSN
0163-2116

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## Abstract Proliferating cells express the pyruvate kinase isoenzyme type M2 (M2‐PK). This enzyme exists as an active tetramer and an inactive dimer. The dimeric form is predominantly found in tumor cells and is therefore termed Tumor M2‐PK (TuM2‐PK). TuM2‐PK molecules are released into the periph