## Abstract Nucleophilic displacement of activated nitro groups by ^18^Fβfluoride ion is an efficient route to fluorineβ18 labeled aromatics, which can be obtained in the noβcarrierβadded state if required. The basic features of the fluorodenitration process are comparatively evaluated, and the in
The preparation of F18-labelled aryl fluorides
β Scribed by T. Nozaki; Y. Tanaka
- Publisher
- Elsevier Science
- Year
- 1967
- Weight
- 551 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0020-708X
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π SIMILAR VOLUMES
A new route to aryl [18F]fluorides without electron withdrawing ring substituents has been developed. [18F]Fluorobenzaldehydes, prepared from no-carrier-added (NCA) [18F]fluoride using nucleophilic aromatic substitution of fluoro or nitro groups, were decarbonylated using palladium on charcoal (Pd-C
BmMARY N-Fluoropyridinium triflate was labelled with 18P proceeding through N-trimethylsilylpyridinium triflate and [ 18F] F2 diluted to 1% in Ne. A typical experiment afforded this new fluorine-18 transfer reagent with up to 46% radiochemical yield. The specific activity of 18F-labelled N-fluoropyr
A rapid procedure for the synthesis of B-D-glucosyl fluoride labelled with the short-lived, positron-emitting radionuclide, 18F, is described. Accelerator produced 18F as Ag18F is reacted with tetra-0-acetyl-a-D-glucoayl bromide, and the product is hydrolyzed with NaOMe producing 18F-6-D-glucooyl fl