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Aryl trimethylammonium trifluoromethanesulfonates as precursors to aryl [18F]fluorides

โœ Scribed by M.S. Haka; M.R. Kilbourn; G.L. Watkins


Publisher
John Wiley and Sons
Year
1989
Tongue
French
Weight
174 KB
Volume
26
Category
Article
ISSN
0022-2135

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Aryltrimethylammonium trifluoromethanesu
โœ Michael S. Haka; Michael R. Kilbourn; G. Leonard Watkins; Steven A. Toorongian ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 444 KB ๐Ÿ‘ 1 views

Aromatic nucleophilic substitution of various trimethylammonium trifluoromethanesulfonates with [18F]fluoride has been evaluated. Fluorinations were studied over a temperature range of 45-165"C, with decay corrected yields ranging from 20-80%. [ I 8F]GBR 131 19, 1-[2-[(4-[~~F]fluorophenyl)(phenyl)me