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Preparation of 18F-labelled N-fluoropyridinium triflate

โœ Scribed by Franz Oberdorfer; Evelyn Hofmann; Wolfgang Maier-Borst


Publisher
John Wiley and Sons
Year
1988
Tongue
French
Weight
289 KB
Volume
25
Category
Article
ISSN
0022-2135

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โœฆ Synopsis


BmMARY N-Fluoropyridinium triflate was labelled with 18P proceeding through N-trimethylsilylpyridinium triflate and [ 18F] F2 diluted to 1% in Ne. A typical experiment afforded this new fluorine-18 transfer reagent with up to 46% radiochemical yield. The specific activity of 18F-labelled N-fluoropyridinium trif late was determined by iodometric titration to be in the range of 4 ~1 0 ' ~ mq/Bq (1.5 mg/mci i 1.67 -10'~ ci/rn) .


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