✦ LIBER ✦

The genetic variant a of human alpha 1-acid glycoprotein limits the blood to brain transfer of drugs it binds

✍ Scribed by P. Jolliet-Riant; M.F. Boukef; J.C. Duché; N. Simon; J.P. Tillement

Book ID: 117175576
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 570 KB
Volume: 62
Category: Article
ISSN: 0024-3205
DOI: 10.1016/s0024-3205(98)00061-7

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The genetic variant A of human alpha 1-a

The genetic variant A of human alpha 1-acid glycoproteln limits the blood to brain transfer of drugs It binds — Pharmacological consequences

✍ P. Jolliet; M.F. Boukef; J.C. Duche; N. Simon; J.P. Tillement 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 179 KB

Selectivity in the binding of psychotrop

Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein

✍ C. B. Eap; C. Cuendet; P. Baumann 📂 Article 📅 1988 🏛 Springer-Verlag 🌐 English ⚖ 672 KB

Selective binding of imatinib to the gen

Selective binding of imatinib to the genetic variants of human α1-acid glycoprotein

✍ Ilona Fitos; Júlia Visy; Ferenc Zsila; György Mády; Miklós Simonyi 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 772 KB

Development of a novel probe for measuri

Development of a novel probe for measuring drug binding to the F1*S variant of human alpha 1-acid glycoprotein

✍ Lawrence P. Cogswell III; Douglas E. Raines; Sonali Parekh; Oliver Jonas; John E 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 305 KB

A novel probe was developed to measure drug association with the F1\*S variant of the human serum protein alpha 1-acid glycoprotein (AGP). The molecule 2hydroxy-3,5-diiodo-N-[2(diethylamino)ethyl]benzamide (DEDIC) binds to AGP, quenching its native ¯uorescence. This quenching was ®tted to a two-site

Selective binding interactions of deramc

Selective binding interactions of deramciclane to the genetic variants of human α1-acid glycoprotein

✍ Ilona Fitos; Júlia Visy; Miklós Simonyi; György Mády; Ferenc Zsila 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 963 KB

Auramine O as a fluorescent probe for th

Auramine O as a fluorescent probe for the binding of basic drugs to human α1-acid glycoprotein (α1-AG) The development of a simple fluorometric method for the determination of α1-AG in human serum

✍ Yuichi Sugiyama; Yasuyuki Suzuki; Yasufumi Sawada; Seiji Kawasaki; Tomoe Beppu; 📂 Article 📅 1985 🏛 Elsevier Science 🌐 English ⚖ 757 KB