𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The (2-Cyano-1-phenyl)ethoxycarbonyl (CPEOC) Group-A New Protecting Group for Oligoribonucleotide Synthesis

✍ Scribed by Münch, Ursula; Pfleiderer, Wolfgang

Book ID
118243996
Publisher
Taylor and Francis Group
Year
1997
Tongue
English
Weight
311 KB
Volume
16
Category
Article
ISSN
0732-8311

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

(Butylthio)carbonyl Group: A New Protect
(Butylthio)carbonyl Group: A New Protecting Group for the Guanine Residue in Oligoribonucleotide Synthesis
✍ Masayo Fujii; Shunichi Yamakage; Hiroshi Takaku; Tsujiaki Hata 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 281 KB

The protection of the 06-amide and N2-amino groups of guanosine with the (butylthio)carbonyl group is described. This group could be rapidly introduced in good yields and removed very easily under the conventional deprotective condition for the exo-amino acyl groups of other nucleoside bases.

1,1,1,3,3,3-Hexafluoro-2-propyl group as
1,1,1,3,3,3-Hexafluoro-2-propyl group as a new phosphate protecting group for oligoribonucleotide synthesis in the phosphotriester approach
✍ Shunichi Yamakage; Masayo Fujii; Hiroshi Takaku; Masaru Uemura 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 508 KB

The 1,1,1,3,3,3-Hexafluoro-2-propyl group can be used as a new class of phosphate protecting group for the protecting group of internucleotidic bonds in the oligonucleotide synthesis by the phosphotriester approach . This protecting group is removed easily by treatment with 0 .3 M N 1 ,N 1 ,N 3 ,N''

Nucleotides. Part LXXIII : Oligoribonucl
Nucleotides. Part LXXIII : Oligoribonucleotide Synthesis with the (2-Cyano-1-phenylethoxy)carbonyl (2c1peoc) Group for the 5′-Hydroxy Protection
✍ Ursula Münch; Wolfgang Pfleiderer 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 German ⚖ 292 KB

## Abstract The (2‐cyano‐1‐phenylethoxy)carbonyl (2c1peoc) group was developed as a new base‐labile protecting group for the 5′‐OH function in solid‐phase synthesis of oligoribonucleotides __via__ the phosphoramidite approach. The half‐lives of its __β__‐elimination process by 0.1M DBU (1,8‐diazabi