𝔖 Bobbio Scriptorium
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A new 2′-hydroxyl protecting group for the automated synthesis of oligoribonucleotides

✍ Scribed by Rastogi, Himanshu; Usher, David A.

Book ID
111860939
Publisher
Oxford University Press
Year
1995
Tongue
English
Weight
612 KB
Volume
23
Category
Article
ISSN
0305-1048

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(Butylthio)carbonyl Group: A New Protect
(Butylthio)carbonyl Group: A New Protecting Group for the Guanine Residue in Oligoribonucleotide Synthesis
✍ Masayo Fujii; Shunichi Yamakage; Hiroshi Takaku; Tsujiaki Hata 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 281 KB

The protection of the 06-amide and N2-amino groups of guanosine with the (butylthio)carbonyl group is described. This group could be rapidly introduced in good yields and removed very easily under the conventional deprotective condition for the exo-amino acyl groups of other nucleoside bases.