Synthesis of pentathymidylate using a 4-
โ
Kohji Seio; Mitsuo Sekine
๐
Article
๐
2001
๐
Elsevier Science
๐
French
โ 82 KB
A phosphoramidite unit having 4-monomethoxytritylthio as a new 5%-hydroxyl protecting group was prepared and employed in oligonucleotide synthesis. The new phosphoramidite enabled the synthesis of oligonucleotides without the use of acids such as TFA or DCA.