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Oligonucleotide synthesis. Part 21. Synthesis of ribooligonucleotides using the 4-methoxybenzyl group as a new protecting group for the 2'-hydroxyl group

โœ Scribed by Takaku, Hiroshi; Kamaike, Kazuo; Tsuchiya, Hiromichi


Book ID
126202427
Publisher
American Chemical Society
Year
1984
Tongue
English
Weight
808 KB
Volume
49
Category
Article
ISSN
0022-3263

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Synthesis of pentathymidylate using a 4-
โœ Kohji Seio; Mitsuo Sekine ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 82 KB

A phosphoramidite unit having 4-monomethoxytritylthio as a new 5%-hydroxyl protecting group was prepared and employed in oligonucleotide synthesis. The new phosphoramidite enabled the synthesis of oligonucleotides without the use of acids such as TFA or DCA.