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Oligonucleotide synthesis by the use of a 2-(levulinyloxymethyl)-5-nitrobenzoyl group as the novel base-labile protecting Group for the 5′-hydroxyl groups of ribonucleoside and 2′-deoxyribonucleoside 3′-phosphoramidites

✍ Scribed by Kazuo Kamaike; Hiroaki Takahashi; Takashi Kakinuma; Kimio Morohoshi; Yoshiharu Ishido


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
228 KB
Volume
38
Category
Article
ISSN
0040-4039

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Chemical properties of 4,5-di(ethoxycarb
✍ Boleslaw Karwowski; Kohji Seio; Mitsuo Sekine 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 524 KB

## Abstract magnified image We describe basic chemical properties of 4,5‐di(ethoxycarbonyl)‐1,3‐dioxolan‐2‐yl (DECDO) in view of its use as a protecting group for the 2′‐hydroxyl function of ribonucleosides. The DECDO group is found to be compatible with the DMTr strategy for the currently‐used ol