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(Butylthio)carbonyl Group: A New Protecting Group for the Guanine Residue in Oligoribonucleotide Synthesis

โœ Scribed by Masayo Fujii; Shunichi Yamakage; Hiroshi Takaku; Tsujiaki Hata

Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
281 KB
Volume
28
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

The protection of the 06-amide and N2-amino groups of guanosine with the (butylthio)carbonyl group is described. This group could be rapidly introduced in good yields and removed very easily under the conventional deprotective condition for the exo-amino acyl groups of other nucleoside bases.

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