The protection of the 06-amide and N2-amino groups of guanosine with the (butylthio)carbonyl group is described. This group could be rapidly introduced in good yields and removed very easily under the conventional deprotective condition for the exo-amino acyl groups of other nucleoside bases.
Methoxyethoxymethyl group for the protection of uracil residue in oligoribonucleotide synthesis
β Scribed by Hiroshi Takaku; Souichi Ueda; Tsunehiko Ito
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 295 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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