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The use of labile base protecting groups in oligoribonucleotide synthesis

✍ Scribed by Carole Chaix; Didier Molko; Robert Téoule

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
262 KB
Volume
30
Category
Article
ISSN
0040-4039

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Incompatibility of acid-labile 2′ and 5′
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✍ Chris Christodoulou; Sudhir Agrawal; Michael J. Gait 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 152 KB

Cleavage of 2'-0-tetrahydropyranyl groups from ribonucleoside derivatives used in solid-phase oligoribonucleotide synthesis takes place to an unacceptable extent during treatment with protic acid to remove 5'-O-pixyl groups.