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Nucleotides. Part 73. Oligoribonucleotide Synthesis with the (2-Cyano-1-phenylethoxy)carbonyl (2c1peoc) Group for the 5′-Hydroxy Protection.

✍ Scribed by Ursula Muench; Wolfgang Pfleiderer

Publisher
John Wiley and Sons
Year
2003
Weight
52 KB
Volume
34
Category
Article
ISSN
0931-7597

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Use of the 2-dansylethoxycarbonyl (= 2-{[5-(dimethylan1ino)naphthalen-I-yl]sulfonyl}ethoxycarbonyl; Dnseoc) group as an intermediate 5'-OH protecting group in oligodeoxyribonucleotide synthesis using the automated phosphoramidite approach is described in a model study to an alternative strategy in R