## Abstract The synthesis of new bioisosteric analogues of farnesyl pyrophosphate where a vinyl pyrophosphonate replaced the pyrophosphate moiety is described. These compounds have been prepared using a Horner–Wadsworth–Emmons procedure and a modified Michelson reaction. They have been evaluated fo
✦ LIBER ✦
Synthesis Routes Towards the Farnesyl Protein Transferase Inhibitor ZARNESTRATM
✍ Scribed by Patrick R. Angibaud; Marc G. Venet; Walter Filliers; Rudy Broeckx; Yannick A. Ligny; Philippe Muller; Virginie S. Poncelet; Dave W. End
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 159 KB
- Volume
- 2004
- Category
- Article
- ISSN
- 1434-193X
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