## Abstract [2‐^13^C, 2‐^14^C]2‐Aminoethanol hydrochloride was prepared in good yield from Na\*CN in a two step sequence by first converting the Na\*CN to OHCH~2~\*CN and then reducing the nitrile directly with a solution of borane‐tetrahydrofuran complex. The reaction procedure was simple and the
Synthesis of triple (13C2, 15N), single (14C), and double (14C2) labeled trimetrexate
✍ Scribed by James L. Hicks; Jon D. Hartman; Richard W. Skeean; C. C. Huang; John A. Kepler; Chun-Hua Liang
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- French
- Weight
- 587 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
A method was developed for the synthesis of triple (^13^C~2~, ^14^N) labeled trimetrexate. A method for single carbon‐14 labeled synthesis is also described. Modifications of the triple labeled synthesis with carbon‐14 produced a doubled carbon‐14 labeled trimetrexate.
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