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Synthesis of 14C-labelled isotope-isomeric alkanes. I n-heptane-1-14C and -2-14C

✍ Scribed by Ioana Bally; Eugenia Gǎrd; Elieabeta Ciornei; Maria Biltz; A. T. Balaban

Publisher
John Wiley and Sons
Year
1975
Tongue
French
Weight
301 KB
Volume
11
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

The synthesis of n‐heptane‐1‐^14^C is described. starting from ^14^CH~3~I via (^14^CH~3~) ~2~Cd and caproyl chloride; for obtaining n‐heptane‐2‐^14^C, n‐pentyl bromide is converted into the Grignard reagent, carbonated with ^14^CO~2~, and the resulted coproic acid is converted into its chloride and treated with dimethyloadmium. In both cases the labelled n‐heptan‐2‐one is finally reduced to labelled n‐heptane by the Kishner‐Wolff method.

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