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Synthesis of Spiro[benzazepine-2,4‘-piperidine]

✍ Scribed by Cossy, J.; Poitevin, C.; Gomez Pardo, D.; Peglion, J.-L.; Dessinges, A.


Book ID
127015410
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
123 KB
Volume
63
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Synthesis of Spiro[
✍ J. COSSY; C. POITEVIN; D. GOMEZ PARDO; J.-L. PEGLION; A. DESSINGES 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views

## Synthesis of . -In continuation of a research on biologically active spiroheterocycles, a synthesis of the spirobenzazepine (VIII) is desired. The compound is obtained by a route involving Heck-type cyclization of the monoprotected amine (I) and the formation of the seven-membered ring (VII)