𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of spiro[quinoline-2,4′-piperidines] Heck versus radical reaction

✍ Scribed by Janine Cossy; Christophe Poitevin; Domingo Gomez Pardo; Jean-Louis Peglion; Aimée Dessinges

Book ID
108386669
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
187 KB
Volume
39
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of Spiro[
ChemInform Abstract: Synthesis of Spiro[benzazepine-2,4′-piperidine].
✍ J. COSSY; C. POITEVIN; D. GOMEZ PARDO; J.-L. PEGLION; A. DESSINGES 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views

## Synthesis of . -In continuation of a research on biologically active spiroheterocycles, a synthesis of the spirobenzazepine (VIII) is desired. The compound is obtained by a route involving Heck-type cyclization of the monoprotected amine (I) and the formation of the seven-membered ring (VII)

Synthesis of morphine fragments spiro[be
Synthesis of morphine fragments spiro[benzofuran-3(2H),4′-piperidine] and octahydro-1H-benzofuro[3,2-e]isoquinoline by intramolecular Heck reaction
✍ Chen-Yu Cheng; Jing-Ping Liou; Mei-Jing Lee 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 209 KB

As a better alternative to radical cyclization, 5-(2-bromo-6-methoxyphenoxy)-2-methyl-l,2,3,4,5,6,7,8-octahydroisoquinoline (2) and its 1-oxo analog 3 underwent Pdcatalyzed intramolecular cyclization to give the tetracyclic (ACNO) morphine fragments 5 and 6 respectively. 4-[(2'-Iodo-6'-methoxyphenox