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Synthesis and some chemical properties of piperidine-4-spiro-2′-oxiranes

✍ Scribed by A. M. Zvonok; E. B. Okaev

Book ID
104792683
Publisher
Springer US
Year
1992
Tongue
English
Weight
294 KB
Volume
28
Category
Article
ISSN
0009-3122

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## Synthesis of . -In continuation of a research on biologically active spiroheterocycles, a synthesis of the spirobenzazepine (VIII) is desired. The compound is obtained by a route involving Heck-type cyclization of the monoprotected amine (I) and the formation of the seven-membered ring (VII)