C-a 1 k y 1 i o d i d e s f o l l o w e d b y a c i d i c h y d r o l y s i s a n d t h e l a b e l l e d a m i n o a c i d s w e r e o b t a i n e d i n 1 0 -5 5 X r a d i o c h e m i c a l y i e l d . L-C3-"C+ A L a n i n e a n d L -C 3 -1 1 C l p h e n y l a l a n i n e w e r e o b t a i n e d i
Synthesis of racemic [3-11C]phenylalanine and [3-11C]DOPA
✍ Scribed by Christer Halldin; Bengt Långström
- Publisher
- Elsevier Science
- Year
- 1984
- Weight
- 331 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0020-708X
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The synthesis of C3-1 lClphenylpyruvic acid, starting with 11C02, is reported. This a-keto acid was prepared via a condensation reaction, using C 1 'Clbenzaldehyde (prepared as described elsewhere), and 2-phenyl-5-oxazolone, using diazabicyclooCtane (DABCO) da a base. The condensation product , [a-l
## Abstract The synthesis of racemic [α‐^11^C]amphetamine and [α‐^11^C]‐phenethylamine from on‐line produced [^11^C]nitroethane and [^11^C]nitromethane, respectively, is described. The condensations of nocarrier‐added [^11^C]nitroalkanes with benzaldehyde to form [β‐^11^C]β‐nitrostyrenes were inves
## Abstract The synthesis of racemic [2‐^11^C]phenylglycine, starting with ^11^CO~2′~ is reported. The [^11^C]benzaldehyde, prepared as previsously described in a two‐step reaction from the corresponding [^11^C]benzoic acid salt, was used in a modified Bücherer‐Strecker reaction. The radiochemical