Synthesis of 14C-radiolabelled trimethyllead chloride
β Scribed by J S Blais; W D Marshall
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 740 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0268-2605
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Radiolabelled [^14^C]entecavir, (**1**), was prepared in 12 steps from (1S,2R,3S,5R)β3β(benzyloxy)β2β(benzyloxymethyl)β6βoxaβbicyclo[3.1.0]hexane **2**. The chemical yield of [^14^C]entecavir was 14% from the epoxide **2**. Introduction of [^14^C] radiolabel was achieved by elaboration
The stereoselective total synthesis of the antimalarial agent 14C-(+)-artemisinin (l), incorporating I4C at C-16 (C-9 methyl) is reported, in 18% radiochemical yield from acid 3.
## Abstract Ractopamine HCl was uniformly labeled with carbonβ14 in one of two phenyl rings as a requirement for animal metabolism studies. The sixβstep synthesis was completed in a 14% yield. Product instability on silica gel complicated purification, but development of a chromatographic method af
## Abstract Our research group is currently exploring the use of hypocrellins as potential photosensitizers for photodynamic therapy (PDT). The purpose of this study is to investigate the synthesis and biodistribution of ^14^Cβlabelled Hypocrellin B. Radiolabelled hypocrellinβB (HB) with the ^14^C
The synthesis of [4-14 C]-pelargonidin chloride and [4-14 C]-delphinidin chloride via [formyl-14 C]-2-(benzoyloxy)-4,6-dihydroxybenzaldehyde, o,4-diacetoxyacetophenone and o,3,4,5-tetraacetoxyacetophenone is described. The first step comprised labelling of the carbonyl group of 2-(benzoyloxy)-4,6-di