Convenient methods for the selective hydrolysis of the thioester groups of dithiopyr to the corresponding carboxylic acid are described. 2-@ifluoromethyl)-4-(2-methylpropyl)-5-[ (methylthio)carbnyl] -6-(trifluoromethyl)-3-pyridine-4-~~C-carboxylic acid (2) was obtained by simple potassium hydroxide
Synthesis of 13C-enriched and 14C-labelled dithiopyr
✍ Scribed by Mohammad E. Mehrsheikh; Lane A. Clizbe; Harbhajan Singh; Wr Purdum
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 314 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
This report describes the synthesis of the ^13^C‐enriched and ^14^C‐labelled title compound starting from isotopically labelled isovaleraldehyde.
📜 SIMILAR VOLUMES
## Abstract ^13^C‐ and ^14^C‐uniformly labelled catechol was synthesized from phenol in three steps. Phenol was derivatized with 2‐chloro‐5‐nitrobenzophenone in THF containing NaH, followed by __ortho__‐hydroxylation with 35% aqueous H~2~O~2~ in sulphuric acid/glacial acetic acid solution, and by c
The syntheses of '%-ring labeled levamisole ([-)-2,3,5,6-tetrahydr0-6-phenyl[~'C-UL]imidazo(Z, 1b]thiole) from acetophenone-ring-UL-l'C in 5 steps plus resolution with a 7.5% overall yield, and %,-ring labeled tetramisole ([i]-2,3,5,6-tetrahydro-6-phenyif3 S ]imidaz0[2,?-bjthiazole) from benzene-'%,
## Abstract Catechol‐U‐^14^C and hydroquinone‐U‐^14^C were prepared from phenol‐U‐^14^C by mononitration followed by chromatographic separation of __o__‐ and __p__‐nitrophenol‐U‐^14^C. The nitrophenols were separately hydrogenated, and the resulting aminophenols were converted by diazotization foll
The enzyme catalyzed displacement o f the methyl s u l f o n y l group from pentachlorophenyl methyl sulfone, the pchloroperoxybenzoic a c i d oxidation of methyl mercaptan and the reaction o f m e t h y l l i t h i u n with sulfur dioxide are methods described f o r the synthesis o f i s o t o p i
## Abstract ^3^H‐Sch 58235 was prepared at a specific activity of 29.1 Ci/mmol by Ir(COD)(Cy~3~P)PyPF~6~ catalysed exchange with tritium gas. ^14^C‐Sch 58235 was prepared in three steps from __p__‐hydroxy[ring‐U‐^14^C]benzaldehyde with an overall radiochemical yield of 21%. ^13^C~6~‐Sch 58235 was s