## Abstract A tacile synthesis of 2‐nitrobenzaldehyde‐__formyl__‐^13^__C__ was developed. This compound was converted to the labelled antiarrhythmic agent, encainide‐^13^__C__ hydrochloride, 4‐methoxy‐__N__‐[2‐[2‐(1‐methyl‐2‐piperidinyl)ethyl‐**1**‐^13^__C__]phenyl]benzamide hydrochloride.
Synthesis of 13C-bucindolol hydrochloride
✍ Scribed by T. M. Dolak; W. E. Kreighbaum; P. C. Johnson; R. R. Covington
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- French
- Weight
- 177 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
hydrochloride, a novel beta-adrenergic antagonist, was synthesized in our laboratory for metabolic studies. ride from 2-hydroxybenzonitrile-[ ~y a n o -~~C ] utilizing 13C-copper(I) cyanide as an isotopic starting material is described.
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