Two 14C preparations o f t h e Hz-antagonist e t i n t i d i n e hydrochloride a r e reported. I n one, t h e l a b e l I s introduced by r e a c t i n g [1-I4C] propargylamine w i t h t h e a p p r o p r i a t e i s o t h i ourea, f o l l o w e d by h y d r o c h l o r i d e formation. This a f f
Synthesis of 14C labelled drotaverinum hydrochloride
✍ Scribed by E. Koltai; D. Bánfi; J. Engler; J. Volford; Z. Mészáros
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- French
- Weight
- 182 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Drotaverinum hydrochloride was labelled with 14C isotope in position 1 of the isoquinoline ring. A rapid synthesis with high radiochemical yield was elaborated. ~ * Kl'CN was prepared by BBnfi's method5 4C -Drotaverinwn Hydrochloride
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