๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Preparation of 14C- labelled trazodone hydrochloride

โœ Scribed by K. Sugiyama; S. Kono; C. Yamato; T. Fujita

Publisher
John Wiley and Sons
Year
1973
Tongue
French
Weight
121 KB
Volume
9
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

โœฆ Synopsis

PSEP4R1TITI 3F 14C-L4PELLEC TPAZODQNE HYDSOCHLO!lIX, R e c e i v e d on J u n e 6 , 1 9 7 3 Trazodone hydrochloride*, 2-I3-[(4-m-chlorophenyl)-lpiperazinyll propyll s-triazolo-[4,3-a1 -pyridine-3 (2H) -one hydrochloride is a new psycotropic drug derived from triazolopyridine (') and has been extensively investigated in the pharmacological and clinical fields(21 3 r ' ) .

* This name has been reported as the nonproprietary name in the A mixture of

๐Ÿ“œ SIMILAR VOLUMES

Synthesis of 14C labelled drotaverinum h
Synthesis of 14C labelled drotaverinum hydrochloride
โœ E. Koltai; D. Bรกnfi; J. Engler; J. Volford; Z. Mรฉszรกros ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 182 KB

Drotaverinum hydrochloride was labelled with 14C isotope in position 1 of the isoquinoline ring. A rapid synthesis with high radiochemical yield was elaborated. ~ \* Kl'CN was prepared by BBnfi's method5 4C -Drotaverinwn Hydrochloride

Synthesis of 14C-labelled etintidine hyd
Synthesis of 14C-labelled etintidine hydrochloride
โœ Stephen M. Stefanick; Charles F. Kasulanis; Seymour D. Levine; Arthur C. Fabian ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 279 KB

Two 14C preparations o f t h e Hz-antagonist e t i n t i d i n e hydrochloride a r e reported. I n one, t h e l a b e l I s introduced by r e a c t i n g [1-I4C] propargylamine w i t h t h e a p p r o p r i a t e i s o t h i ourea, f o l l o w e d by h y d r o c h l o r i d e formation. This a f f

Synthesis of [14C]-labelled vardenafil h
Synthesis of [14C]-labelled vardenafil hydrochloride and metabolites
โœ D. Seidel; P. Brehmer; Y. Schoof; U. Weinberg; M. Nowakowski ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 179 KB

## Abstract For studies of pharmacokinetics and drug metabolism of the new orally active, selective phosphodiesterase type V (PDE V) inhibitor vardenafil (Levitra^ยฎ^), the ^14^Cโ€labelled version was synthesised. Starting from the cyanation of 2โ€iodophenol with K^14^CN, an 8โ€step synthesis led to tw

Preparation of 14C-labelled dimethylsila
Preparation of 14C-labelled dimethylsilane-1,1-diol
โœ J. A. Cella; J. C. Carpenter ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 199 KB ๐Ÿ‘ 1 views

## Abstract The preparation of ^14^Cโ€labelled dimethylsilaneโ€1, 1โ€diol in two steps from ^14^Cโ€labelled diphenyldimethylsilane is described. Aluminum chloride catalyzed protodesilylation of diphenyldimethylsilane with HCl in dichloromethane or dimethyldichlorosilane at 0โ€“5ยฐC affords labelled dimeth