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Synthesis of 14C-labelled 2,4,-diamino-5-phenylthiazole hydrochloride (amiphenazole)

✍ Scribed by Jeffrey G. Adams; Paul J. Nicholls; Hywel Williams

Publisher
John Wiley and Sons
Year
1976
Tongue
French
Weight
155 KB
Volume
12
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

The synthesis of 2,4‐diamino‐5‐phenylthiazole hydrochloride labelled with carbon – 14 in the 2‐position has been effected whereby the ^14^C‐label was introduced in the last step. The overall yields were 34.5% (gravimetrically) and 32.8% (radiochemically).

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