## Abstract The synthesis of 2,4‐diamino‐5‐phenylthiazole hydrochloride labelled with carbon – 14 in the 2‐position has been effected whereby the ^14^C‐label was introduced in the last step. The overall yields were 34.5% (gravimetrically) and 32.8% (radiochemically).
Labelling of 2-hydroxy -5-carbomethoxybenzyloxyamine hydrochloride with 14c isotope
✍ Scribed by J. Engler; E. Kasztreiner
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- French
- Weight
- 181 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
Radioisotopic labelling of a novel histamine level reducing and antiinflammatory agent is described. The 2‐hydroxy‐5‐carbomethoxybenzy ‐^14^C‐oxyamine hydrochloride was prepared for the purpose of radioisotopic indication and further for pharmacological and action mechanism studies.
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## Abstract The synthesis of n‐heptane‐1‐^14^C is described. starting from ^14^CH~3~I via (^14^CH~3~) ~2~Cd and caproyl chloride; for obtaining n‐heptane‐2‐^14^C, n‐pentyl bromide is converted into the Grignard reagent, carbonated with ^14^CO~2~, and the resulted coproic acid is converted into its
Synthesis of I4C-Labeled Pramiracetam Hydrochloride, E-[2-(Bis[ 1-me thyle thyl 1 aminole thyl ] -2-0x0-l -p y r r o l i d i n eac.etamide-a-14C Hydrochloride, CI-879 Hydrochloride1