𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of 4-fluoro-4′-trifluoromethylbenzophenone guanylhydrazone hydrochloride labeled with 14C

✍ Scribed by Theodore S. T. Wang; Rashid A. Fawwaz

Publisher
John Wiley and Sons
Year
1985
Tongue
French
Weight
181 KB
Volume
22
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of 14C-labelled 2,4,-diamino-5
Synthesis of 14C-labelled 2,4,-diamino-5-phenylthiazole hydrochloride (amiphenazole)
✍ Jeffrey G. Adams; Paul J. Nicholls; Hywel Williams 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 155 KB

## Abstract The synthesis of 2,4‐diamino‐5‐phenylthiazole hydrochloride labelled with carbon – 14 in the 2‐position has been effected whereby the ^14^C‐label was introduced in the last step. The overall yields were 34.5% (gravimetrically) and 32.8% (radiochemically).

Synthesis of 4′-iodo-4′-[14-14C]-deoxydo
Synthesis of 4′-iodo-4′-[14-14C]-deoxydoxorubicin hydrochloride (FCE 21954)
✍ Erminia Fontana; Antonino Suarato; Michele Caruso; Gian Piero Vicario 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 French ⚖ 242 KB

The synthesis of 4' -iodo-4 l -[ 14-l4C1 -deoxydoxorubicin hydrochloride (PCE 21954) in five steps is described. 4 -Epi-N-trif luoroacetyl-[ 14-14C] -daunorubicin has been employed as starting material. substitution of C-4l-OH with iodine and subsequent hydroxylation of the side chain, via the 14-br

Synthesis of 14C-labelled (S)-(+)-2-[4-(
Synthesis of 14C-labelled (S)-(+)-2-[4-(p-fluorobenzoyl)-1-piperidyl]-1-naphthylethanol hydrochloride
✍ Norio Karibe; R. M. Rosser; Masataka Ueda; Hachiro Sugimoto 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 236 KB

## Abstract ^14^C‐labelled (S)‐(+)‐2‐[4‐(p‐fluorobenzoyl)‐1‐piperidyl]‐1‐naphthylethanol hydrochloride (5), an anti‐ischemic drug, was synthesized for studying the pharmacokinetic profiles of the compound in four steps using 2‐[carbonyl‐^14^C]acetonaphthone (1) as a labelled starting material.

Labelling of neuroleptic butyrophenones.
Labelling of neuroleptic butyrophenones. III. Synthesis of 2′-amino-4′-fluoro-4-[4-hydroxy-4-(3-trifluoromethylphenyl)piperidino-2-14C] - butyrophenone
✍ Iwao Nakatsuka; Kazuo Kawahara; Akira Yoshitake 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 474 KB

## Abstract 2′‐Amino‐4′ ‐fluoro‐4‐(4‐hydroxy‐4‐) (3‐trifluoromethylphenyl) ‐ piperidino‐2‐^14^Cbutyrophenone [ID‐4708‐ (piperidine‐^14^C]), a neuroleptic agent, was synthesized for use in metabolic studies. The synthesis was achieved by the reaction scheme shown in Fig. 1. 1‐Benzyl‐4‐piperidone‐2‐^