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Synthesis and characterization of carbon-14 labelled 4, 4′- diaminodiphenyl sulfone (dapsone-14C; DDS-14C)

✍ Scribed by C. E. Blackburn; A. J. Glazko

Publisher
John Wiley and Sons
Year
1972
Tongue
French
Weight
206 KB
Volume
8
Category
Article
ISSN
0022-2135

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✦ Synopsis

SYNTtIESIS AHD CHARACTERIZATION

OF CARBON-14 LABELLED 4,4'-DIAMINODIPHENYL SULFONE (DAPSONE-l4C; D 3 S -1 4 C > , C.E. B l a c k b u r n and A.J. G l a z k o . D e p a r t m e n t o f P h a r m a c o l o g y . D i v i s i o n of S c i e n t i f i c and M e d i c a l Affairs. P a r k e -D a v i s C o m p a n y , A n n A r b o r , M i c h i g a n , U. S . A. R e c e i v e d on J u l y 9, 1971.

SUMMARY

4,4 ' -D i a m i n o d i p h e n y l -1 4 C s u l f o n e * ( D D S -1 4 C I was s y n t h e s i a e d i n f o u r s t e p s . U n i f o r m l y c a rbon-14 l a b e l l e d a n i l i n e h y d r o c h l o r i d e was f i r s t a c e t y l a t e d t o y i e l d a c e t a n i l i d e (phenyl-"CI.

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