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Stimulation of binding of benzo[a]pyrene metabolites to DNA by diet-induced peroxidative stress

✍ Scribed by G.Y. Kwei; L.F. Bjeldanes

Book ID
119160058
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
499 KB
Volume
28
Category
Article
ISSN
0278-6915

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## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy