Rat liver microsome-mediated binding of
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M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes
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Article
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1976
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John Wiley and Sons
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French
β 422 KB
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## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8βdihydroβ7,8βdihydroxy