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Binding of benzo(a)pyrene metabolites to cellular DNA in perfused rat lungs

✍ Scribed by B. Deckers-Schmelzle; E. Klaus; R. Kahl; G. F. Kahl

Book ID
112341796
Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
445 KB
Volume
303
Category
Article
ISSN
0028-1298

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✍ M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 French βš– 422 KB πŸ‘ 1 views

## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy