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UDP-glucuronosyl transferase and the conjugation of benzo(a)pyrene metabolites to DNA

✍ Scribed by William E. Fahl; Anna L. Shen; Colin R. Jefcoate

Book ID
118312404
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
466 KB
Volume
85
Category
Article
ISSN
0006-291X

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Rat liver microsome-mediated binding of
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✍ M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 French βš– 422 KB πŸ‘ 1 views

## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy