๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Solid-phase synthesis of pseudo-complementary peptide nucleic acids

โœ Scribed by Komiyama, Makoto; Aiba, Yuichiro; Ishizuka, Takumi; Sumaoka, Jun


Book ID
109946619
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
261 KB
Volume
3
Category
Article
ISSN
1750-2799

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Solid-Phase synthesis of peptide nucleic
โœ Dr. Leif Christensen; Richard Fitzpatrick; Brian Gildea; Kenneth H. Petersen; He ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 638 KB

Peptide nucleic acids (PNA) were synthesized by a modified Merrifield method using several improvements. Activation by O-[benzotriazol-1-yl]-1,1,3,3-tetramethyluronium hexafluorophosphate in combination with in situ neutralization of the resin allowed efficient coupling of all four Boc-protected PNA

Solid phase synthesis of protected pepti
โœ Oliver Seitz ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 234 KB

Boc/'Z-protected PNA oligomers were synthesised on solid phase. The use of the allylic HYCRON resin allowed for the application of both Boc-and Fmoc-protecting groups. Highest yields were obtained when the monomeric building block was synthesised on solid phase rather than loaded as preformed unit.

Solid-Phase Synthesis of Peptide-Derived
โœ Vibhakar J. Shah; Robert Cerpa; Irwin D. Kuntz; Jr.; George L. Kenyon ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 207 KB

The first solid-phase synthesis of novel peptide-derived enantiospecific nucleic acid analogs (PDNAs), employing all three stereoisomers of 4-(N 9 -adeninyl)-2-amino(t-boc)-butyric acid as ADNA (amino acid-derived nucleoside analogs) monomers has been described. The preliminary melting temperature (

Nucleic acid analog peptide (NAAP). Soli
โœ Masayuki Fujii; Koji Yamamoto; Jinsai Hidaka; Takayuki Ohtsu ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 174 KB

Solid phase synthesis of a nucleic acid analog peptide (NAAP), as a substitute for antisense or triple-helix forming oligonucleotide, is described. The N-protected amino acid monomer was prepared starting from 3'-azido-3'-deoxythymidine (AZT) in 20 % overall yield. Condensation of the amino acid mon