๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Synthesis of peptide nucleic acids (PNA) by submonomer solid-phase synthesis

โœ Scribed by Lutz S. Richter; Ronald N. Zuckermann


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
250 KB
Volume
5
Category
Article
ISSN
0960-894X

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Solid phase synthesis of protected pepti
โœ Oliver Seitz ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 234 KB

Boc/'Z-protected PNA oligomers were synthesised on solid phase. The use of the allylic HYCRON resin allowed for the application of both Boc-and Fmoc-protecting groups. Highest yields were obtained when the monomeric building block was synthesised on solid phase rather than loaded as preformed unit.

Solid-phase synthesis of peptide nucleic
โœ Gudrun Aldrian-Herrada; Alain Rabiรฉ; Reinhold Wintersteiger; Jean Brugidou ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 227 KB ๐Ÿ‘ 2 views

A new simple solid-phase method has been developed for synthesizing Boc-protected peptide nucleic acid (PNA) monomers. An immobilized backbone 3 was built on Expansin ยฎ resin using an ester disulphide handle: 2-hydroxypropyl-dithio-2%-isobutyric acid (HPDI). The base acetic acids of thymine 5, Z-cyt

Solid-Phase Synthesis of Peptide-Derived
โœ Vibhakar J. Shah; Robert Cerpa; Irwin D. Kuntz; Jr.; George L. Kenyon ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 207 KB

The first solid-phase synthesis of novel peptide-derived enantiospecific nucleic acid analogs (PDNAs), employing all three stereoisomers of 4-(N 9 -adeninyl)-2-amino(t-boc)-butyric acid as ADNA (amino acid-derived nucleoside analogs) monomers has been described. The preliminary melting temperature (